2026 Research Awards

Congratulations to our successful applicants in the 2026 funding round. These awards are made possible by the generosity of our community, helping turn promising research into real-world outcomes that save lives.

The Maureen Ellen James Memorial Award

Suzanah Boyd
Macquarie University

Early Career Researcher Award

Dr Douglas Gaskarth
Monash University

Post Graduate Scholar Award

 

Laura Smith
Melanoma Institute Australia

The John Walter Holland Memorial Award

Rachael Stone
Adelaide University

“We hope this research brings us one step closer to our shared goal of zero deaths from melanoma by helping identify patients at the highest risk of recurrence earlier, enabling more personalised care and ultimately improving patient outcomes.” – Suzanah Boyd

Suzanah Boyd

Maureen Ellen James Memorial Award

Macquarie University

While many patients with Stage II melanoma are cured with surgery alone, some experience disease recurrence despite having no obvious signs of cancer remaining after treatment. This project brings together a multidisciplinary research team from Macquarie University (led by Professor Helen Rizos), Melanoma Institute Australia (led by Professor Georgina Long), and Edith Cowan University (led by Professor Elin Gray).
 
Our aim is to develop a highly sensitive blood test, known as a liquid biopsy, that can detect signs of residual disease before melanoma recurrence becomes clinically apparent. By analysing circulating tumour DNA, DNA methylation patterns, and protein biomarkers in the bloodstream, we hope to create a powerful tool for identifying patients at greatest risk of recurrence and informing more personalised treatment strategies.
 
The study will integrate these molecular markers with established clinical factors to improve the accuracy of recurrence prediction. Combined, these biomarkers could help clinicians intervene earlier when needed while reducing unnecessary treatment for lower-risk patients. Ultimately, this approach aims to improve outcomes and quality of life for people affected by melanoma.

“By understanding why some patients respond differently to therapy, this research may lead to more effective, personalised melanoma treatments and improved patient outcomes in the future.” – Dr Douglas Gaskarth

Dr Douglas Gaskarth

Early Career Researcher Award

Monash University

While targeted therapy has significantly improved outcomes for people with advanced melanoma, biological males remain less likely to respond to treatment and to display poorer survival outcomes than females.

This project investigates why these differences occur by examining the role of the androgen receptor – a protein activated by male sex hormones such as testosterone – in driving resistance to MAPK inhibitors, a common targeted therapy for melanoma. Using advanced spectral flow cytometry, we will analyse how cancer cells, immune cells and surrounding support cells within the tumour microenvironment respond to treatment in both male and female melanoma models.

By identifying the cellular mechanisms that contribute to treatment resistance, we aim to uncover new therapeutic targets that could improve responses to therapy, reduce sex-based disparities in melanoma outcomes, and support the development of more personalised treatment for patients.

“My hope is that this research will contribute to a future where every patient with melanoma receives the treatment most likely to benefit them. By improving our understanding of how DNA methylation influences response and resistance to immunotherapy, this work aims to support more personalised treatment decisions and inform the development of new therapeutic strategies for patients who do not currently respond to existing therapies.” – Laura Smith

Laura Smith

Post Graduate Scholar Award

Melanoma Institute Australia

Immunotherapy has significantly improved outcomes for many people with melanoma, but challenges remain in predicting which patients will benefit most from treatment.

This project will investigate how DNA methylation, an epigenetic process that regulates gene activity, influences response and resistance to immunotherapy given before surgery (neoadjuvant immunotherapy) in people with stage III melanoma. By analysing tumour samples collected before and after treatment, researchers will map changes in DNA methylation across the genome and examine their impact on tumour biology.

The study aims to identify epigenetic signatures linked to treatment outcomes, improve our understanding of how melanoma evades the immune system, and identify candidate biomarkers and therapeutic targets. Ultimately, this research seeks to support more personalised treatment approaches and improve outcomes for people affected by melanoma.

I am honoured to be receiving this award and am extremely grateful to the Australian Melanoma Research Foundation for their support in this project. I hope that this research will provide us with new insights into how we can improve the outcome of melanoma patients treated with anti-PD-1 therapy.” – Rachael Stone

Rachael Stone

John Walter Holland Memorial Award

Adelaide University

While immune checkpoint inhibitors have transformed the treatment of advanced melanoma, many patients either do not respond or eventually develop resistance to these therapies. This project will investigate a specialised population of cancer-fighting immune cells known as cytotoxic CD8 T cells and explore how a molecule called CD15s helps these cells migrate from the bloodstream into tumours. Previous research has shown that patients with higher levels of CD15s on their T cells are significantly more likely to respond to immunotherapy and experience longer survival.

This study aims to understand how CD15s expression is regulated by examining the role of dendritic cells, which activate T cells, and the gut microbiome, which is increasingly recognised as an important influence on immune function. By uncovering the biological mechanisms that enhance T cell homing to tumours, this research seeks to identify new strategies to improve immunotherapy responses and increase the number of patients who benefit from treatment.

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