What is melanoma?
Melanoma is one of the three main types of skin cancer. It begins in cells called melanocytes, which produce the pigment melanin. Melanin gives skin its colour and helps protect the skin from ultraviolet (UV) radiation.
The amount of melanin produced varies between people and contributes to differences in skin colour, but any skin type can develop melanoma. Melanoma occurs when melanocytes become abnormal and begin to grow and divide in an uncontrolled way. This can be caused by changes to the DNA within the cells, with UV radiation being an important risk factor for most melanomas.
In its earliest stage, melanoma may be confined to the epidermis, the outermost layer of the skin. As it grows deeper into the skin, it has a greater chance of reaching blood vessels or lymphatic vessels and spreading to nearby lymph nodes or other parts of the body. This is why finding and treating melanoma early is so important.
Development of melanoma
Ultra-violet (UV) radiation from sunlight (and tanning beds) plays a significant role in the development of melanoma and other skin cancers.
Melanoma most often develops on areas of skin exposed to the sun, but it can also occur in areas that receive little or no sun exposure, including the palms of the hands, soles of the feet and under the nails. Less commonly, melanoma can develop in areas such as the eye or mucosal tissues.
Research has found that the rates of melanoma in Australia are higher near the coastline and it is reasoned that this is due to lifestyle factors, outdoor activity and greater sun exposure. The rates are also higher in Australia’s northern states due to the intensity of the sun.
Types of melanoma
Superficial Spreading Melanoma
Approximately 70% of all diagnosed melanomas. It usually occurs in a previously non-cancerous mole. Over time, it can change in colour, itch or develop irregular borders.
Ocular/Uveal Melanoma
This rare and often aggressive type of melanoma occurs within the eye. Symptoms can include blurred vision, flashing lights and shadows. However, it is not uncommon for a patient to experience no symptoms and be diagnosed during a routine eye check. The best strategy for prevention is to wear UV protective sunglasses and a broad brimmed hat.
Acral Lentiginous Melanoma
Also called Subungual melanoma, this type only accounts for around 5% of melanomas but makes up 50% of melanomas in those with darker skin. Most commonly found on the palms of the hands, soles of the feet or under finger and toe nails. In the early stages it is often mistaken for a bruise, blood blister or streak in the nail.
Mucosal Melanoma
Mucosal Melanoma is also rare and accounts for only 1% of all melanomas. As with the skin, melanocytes are present in the mucosal surfaces of the body which line areas such as the sinuses, oral cavity, vagina, bowel and anus. Unlike melanoma of the skin, mucosal melanoma is not linked to sun/UV exposure.
Lentigo Maligna Melanoma
Accounts for around 10% of melanomas and often occurs on the face in sun damaged areas. It often has very irregular borders and varying shades of brown or black.
Nodular Melanoma
Accounting for around 15% of diagnosed melanomas, it is also the most aggressive. It may appear where a mole or lesion did not exist before.
Amelanotic Melanoma
They can appear as a lesion with little or no colour, pink or scar-like. Any lesion that is scar-like or appears next to a previously treated melanoma should be examined immediately.
Melanoma Statistics in Australia
- 1 person dies every 6 hours from melanoma.
- Melanoma is the third most common cancer in Australia.
- Melanoma is the second most common cancer in young Australians (20–39 year olds).
- If detected early more than 90%of melanoma cases can be successfully treated.
- Melanoma rates doubled in the 20 years between 1986 and 2006 and continue to rise. By 2030, a further 14,000 Australians will die, while 205,000 will be diagnosed with the disease.

What to look for
An easy way to detect potentially harmful moles or lesions is to use the ABCDE guidelines.

Prevention and Early Detection
Catching a melanoma early can save lives. Reducing your UV exposure can prevent melanoma.

Treatment
Read our general overview of current treatment options. Always speak with a health professional for the best advice about your circumstances.